![]() ![]() Sculpt: Linear segments and runs available in pendant, recessed, recessed vertical, surface, wall and perimeter mountings. Geometric: Choice of non-rectangular recessed forms compatible with Armstrong ® DESIGNFlex ceiling systems. Howard Hughes Medical Institute, Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA. With their 1.5-wide housing in common, the following luminaire families provide opportunities for harmonized lighting layouts. ![]() A 5' cap binding site on the surface of lambda3 suggests a template retention mechanism by which attachment of the 5' end of the plus-sense strand facilitates insertion of the 3' end of the minus-sense strand into the template channel. This "caged" polymerase has allowed us to visualize the results of several rounds of RNA polymerization directly in the crystals. The crystal structure of the reovirus polymerase, lambda3, determined at 2.5 A resolution, shows a fingers-palm-thumb core, similar to those of other viral polymerases, surrounded by major N- and C-terminal elaborations, which create a cage-like structure, with four channels leading to the catalytic site. The reovirus polymerase and those of other dsRNA viruses function within the confines of a protein capsid to transcribe the tightly packed dsRNA genome segments. Biologically Interesting Molecule Reference Dictionary (BIRD).
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